Testosterone levels in women decline steeply with age during the reproductive years; by the time women reach their late 40, their blood testosterone levels are approximately half what they were in their 20s.[1, 2]
Symptoms of androgen deficiency, including a reduced sense of well-being, dysphoric mood (sadness, depression, anxiety, and irritability), fatigue, decreased libido, hot flashes, bone loss, decreased muscle mass and strength, changes in cognition and memory, and insomnia may occur prior to cessation of menses. Pre-menopausal patients frequently report ‘menopausal symptoms’, most of which are not related to estradiol levels.
Adding testosterone to estrogen therapy in postmenopausal women has beneficial cardiovascular effects and also results in meaningful improvements in sexual function in women not taking estrogen.
Testosterone supplementation in both pre- and postmenopausal women has been shown safe, even in higher doses[7, 8], and shown not to affect the menstrual cycle. It is increasingly used as part of postmenopausal HRT (hormone replacement therapy) regimens. Contrary to old beliefs, testosterone can actually protect against breast cancer. It has been shown that addition of testosterone may counteract breast cell proliferation induced by estrogen/progestogen therapy in postmenopausal women.[11-15]
A notable study investigated the effectiveness of a 3 month continuous testosterone therapy, delivered by subcutaneous implant, on the relief of somatic, psychological and urogenital symptoms in both pre- and post-menopausal patients using the self administered Health-Related Quality of Life (HRQOL) questionnaire called the Menopause Rating Scale (MRS).
Things You Should Know About Menopause
Oh, the joy of being a woman...Menstrual cycles (commonly known as periods) impact women’s lives on a monthly basis starting at puberty for several decades, with the exception of pregnancies when periods cease for a period of 9 months. However, these menstrual cycles do not last forever. Periods will eventually come to a halt permanently, also known as menopause. Understanding menopause is important for men as well as women, since it will affect how men communicate with the women in their lives such as a spouse, mother, sister, female friends, or other relatives during the menopause stage that may last up to a decade. Menopause is popularly correlated to hot flashes and the ceasing of womens’ periods but there is a lot more to it than that. Here are some things you need to know regarding the menopause stages women are going through or will eventually go through and treatments recommended by experts.
Menopause is a cycle middle-aged women go through that has some major hormonal, psychological, and physical changes as their ovaries gradually decrease in estrogen and progesterone production. As we all know very well, getting adequate sleep is very vital to a healthy, functioning life - especially when your body is going through a big transition such as menopause. Many female patients in their late 30s-40s with symptoms of insomnia come in for check-ups and are actually experiencing the beginning stages leading up to menopause, called perimenopause. Hormonal and/or lifestyle changes can impact your sleep pattern. Keep reading to find out more about how perimenopause and menopause can affect your sleep, and some solutions to consider trying!