Ageless Forever Anti-Aging News Blog

Monica Mollica

Monica Mollica

Medical Writer & Nutritionist

MSc in Nutrition

University of Stockholm & Karolinska Institute, Sweden 

   Baylor University, TX, USA

Website URL:

TRT and Fertility – how to get the best of both worlds - part 1

The prevalence of testosterone deficiency (aka hypogonadism or Late Onset Hypogonadism), defined as total testosterone (TT) at or below 300 ng/dl is close to 40% in men aged 45 years and older presenting to primary care offices in the US.[1] Year 2006 is was estimated that more than 13.8 million men over 45 years of age visiting a primary care doctor in the United States have symptomatic androgen deficiency.[1] 
 
A large international web survey using the Aging Males' Symptoms (AMS) questionnaire showed the prevalence of symptomatic testosterone deficiency to be 80% in men aged 16–89 (mean 52 years).[2] It is notable that in the survey 40% of respondent were at younger ages when ‘Late Onset Hypogonadism’ is generally not believed to be occurring.[2] The surprisingly high prevalence of raised scores indicating testosterone deficiency in the younger age groups may be due to the increasing prevalence of conditions in these age groups known to reduce testosterone levels, such as obesity [3-7] and chronic work stress. [8-10] Stress induced cortisol elevation, by increasing SHBG, lowers the free active fraction of testosterone and thereby reduces its action.[11] 
 
This large and rising prevalence of testosterone deficiency is gaining recognition among doctors and patients alike. However, while testosterone replacement therapy (TRT) confers great benefits to men with sup-optimal testosterone levels, it also comes with some side-effects which are especially relevant for men who wish to have a family...Many testosterone users and even clinicians [12] are unaware that exogenous testosterone suppresses the hypothalamic-pituitary-gonadal (HPG) axis and may result in infertility...however, in most cases, TRT induced infertility is reversible. If paternity is of interest to you, read on...
 

Fish oil supplementation - benefits for young healthy adults

Fish oil is well known for protecting against development and progression of cardiovascular disease in high risk individuals, mostly middle-age and older.[1-4] A notable recent study shows that fish oil supplementation also confers health benefits in young healthy adults.[5]

Young healthy males, aged 21-24 years, were given a fish oil supplement providing 2 g EPA and 1 g DHA per day for 3 months. It was found that the fish oil supplementation significantly reduced fasting blood triglycerides (i.e. blood fats) by a whopping 38% (from 86 mg/dL to 54 mg/dL) and also improved the total cholesterol/HDL ratio, by reducing it from 3.25 to 3.05.

Relevance of blood triglycerides and the total cholesterol/HDL ratio for cardiovascular disease

Subscribe to this RSS feed

Dr. Pierce's Medical Organization Affiliations

  • 1-a4m.jpg
  • 2-ACAM.jpg
  • 3-AMMG.jpg
  • 4-American-Board-Anti-Aging-Regenerative-Medicine.jpg
  • 5-AAPMR.jpg
  • 6-acoep.jpg
  • 7-ISSM.jpg
This module can not work without the AcyMailing Component