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TRT – Testosterone Replacement Therapy

Optimal levels of testosterone is critical for both men and women. While being most known for increasing libido and wellbeing, testosterone also have many health promoting effects. 

MEN

Today’s modern lifestyle of high stress levels and poor nutrition habits, lack of regular exercise combined with an increased life expectancy have a significant effect on the male body. Our hormones can become imbalanced over time because hormone-producing glands are being required to work harder and longer. Men need to measure their testosterone levels as well as many other vital hormones such as thyroid, human growth hormone and estrogen.

The imbalance of even one hormone causes imbalance in other hormones and can have a declining domino effect leading to disease, aging, degeneration and breakdowns. Andropause is most commonly regarded as a subtle and gradual onset and very slow progression of symptoms. Not all men show andropause symptoms as they age and not all men show a significant decrease in adrogens as they age. However, men commonly experience a combination of symptoms rather than experiencing all of the symptoms of andropause.

These symptoms include, but aren't limited, to the following:

- Mood Changes (this can also be associated with decreases in intellectual activity, fatigue, depression, loss of enthusiasm for daily life, anger and irritability).
- A decrease in lean body mass, along with decreases in muscle mass, strength and endurance.
- Diminished sexual desire, function and/or sensitivity and erectile quality. A decrease in nocturnal erections is a significant sign of decreased androgens.
- A decrease in body hair.
- A decrease in bone density resulting in osteoporosis. Osteoporosis can often lead to increased incidence of bone fractures and breaks.
- An increase in fat surrounding the internal organs, weight gain and gynecomastia.

We utilize a very simple and very effective screening questionnaire, called the ADAM Questionnaire, which assists the doctor in diagnosing those men who suffer from andropause. However, not all men who screen positively for these symptoms have andropause. The symptoms may be the result of other causes so that a positive diagnosis can only be made with appropriate blood testing.

It is a little-known fact that biological age, not chronological age, determines the aging of our body and its ability to maintain and repair itself. Until around the age of 25, your body is effectively able to regenerate new tissue, create energy and defend itself against disease. But then the balance starts to shift and lose the ability to run up the stairs, hills, or streets the way you did when you were a kid. You wake up tired, and you can’t see or hear or make love as much or as intensely as you did when you were younger.

This healthy balance is more likely to be in your favor when you maintain healthy body chemistry. Long before your body develops degenerative diseases; your body’s chemistry is revealing important clues as to why and how you are losing the youthful function of various organs and systems of your body. Even though you may not show any signs of illness, you may not necessarily be aging optimally. It simply may be that you are not yet exhibiting the advanced signs of accelerated aging. The majority of the American public now realized that an immense chasm exists between medically diagnosed normalcy and optimal health. The problem is the most doctors are reluctant to adopt new sensitive diagnostics and therapies that probe deeper into the biochemical mechanism underlying age-related disorders.

Our proprietary longevity program helps determine the body’s rate of aging, alleviate symptoms of aging, and return the body to a healthier state of functioning. As we age, our “internal milieu” the molecules, nutrients, and chemicals that circulate in and among the cells of the body and determine our chemicals that circulate in and among the cells of the body and determine our genetic potential – becomes deficient in various nutrients and minerals. This can cause a breakdown in functions throughout the body and, over time, promote accelerated aging. Each individual body responds differently to the aging process.

Many signs of aging can be reversed or slowed down with proper analysis and treatment. These include wrinkled skin, poor memory, decreased sex drive, fatigue, increased fat stores, poor digestion, brittle bones, and decreased immunity to disease. Defenses against aging are the latest mechanisms to improve overall health and longevity.

WOMEN

Testosterone is known for being the "male" sex hormone. However, testosterone is equally essential for women's physical and mental health and well-being, albeit in lower amounts than in men. 

Testosterone's role in sexual function and libido is only a small fraction of its physiological effects. Functional androgen receptors (to which testosterone binds) are located in almost all tissues including the breast, heart, blood vessels, gastrointestinal tract, lung, brain, spinal cord, peripheral nerves, bladder, uterus, ovaries, endocrine glands, vaginal tissue, skin, bone, bone marrow, synovium, muscle and adipose tissue. [1]

Testosterone and the pro-androgens decline gradually with aging in both sexes. Pre and post-menopausal women, and aging men, may experience symptoms of androgen deficiency including dysphoric mood (anxiety, irritability, depression), lack of well being, physical fatigue, bone loss, muscle loss, changes in cognition, memory loss, insomnia, hot flashes, rheumatoid complaints, pain, breast pain, urinary complaints, incontinence as well as sexual dysfunction. These symptoms of androgen deficiency are becoming increasingly recognized in women, and successfully treated with testosterone therapy.[2-4]

Even in healthy non-obese postmenopausal women, higher testosterone levels are related to greater maximal aerobic capacity and reduced adiposity, and play a role in the maintenance of a beneficial metabolic state and a healthy body composition and physical function.[5]

At Ageless Forever we measure and monitor testosterone levels, along with many other important hormones, in both men and women.

See our anti-aging news blog for more research based info on Testosterone Replacement Therapy (TRT) for men and women.


References:

 

1.Wilson, C.M. and M.J. McPhaul, A and B forms of the androgen receptor are expressed in a variety of human tissues. Mol Cell Endocrinol, 1996. 120(1): p. 51-7.
2.Glaser, R., A.E. York, and C. Dimitrakakis, Beneficial effects of testosterone therapy in women measured by the validated Menopause Rating Scale (MRS). Maturitas, 2011. 68(4): p. 355-61.
3.Davey, D.A., Androgens in women before and after the menopause and post bilateral oophorectomy: clinical effects and indications for testosterone therapy. Womens Health (Lond Engl), 2012. 8(4): p. 437-46.
4.Goldstat, R., et al., Transdermal testosterone therapy improves well-being, mood, and sexual function in premenopausal women. Menopause, 2003. 10(5): p. 390-8.
5.Casson, P.R., et al., Correlation of serum androgens with anthropometric and metabolic indices in healthy, nonobese postmenopausal women. J Clin Endocrinol Metab, 2010. 95(9): p. 4276-82.

Tags: Testosterone Replacement Therapy Testosterone

Dr. Pierce's Medical Organization Affiliations

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