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Ageless Forever Anti-Aging News Blog

Effects of long-term testosterone treatment on weight loss and waist size in obese men - is TRT the next obesity treatment?

Testosterone, historically believed to be important only for male reproduction and sexuality, has over the past decades transformed from niche hormone to multi-system player.[1] A rapidly accumulating body of research is showing that testosterone is an important metabolic hormone with marked effects on energy metabolism and body composition.[2]
 
In USA, 36% of the adult population are obese (BMI >30), (affecting a similar proportion of men and women) [3], and obesity prevalence is escalating worldwide. According to the McKinsey Global Institute (MGI) report “Overcoming obesity: An initial economic analysis”, obesity is “one of the top three preventable social burdens (along with smoking and violence/war/terrorism) generated by human beings” imposing an estimated annual global direct economic burden amounting to 2 trillion USD.[4] 
 
Obesity treatments with comprehensive lifestyle modification and/or drugs are notorious for their poor long-term efficacy and inability to achieve long-term weight loss maintenance.[5-9] Even with continued lifestyle treatment, significant weight regain occurs.[7, 9, 10] And obesity drugs have side effects which limit their long-term and widespread use. [11, 12] Therefore, new interventions are urgently needed to combat this alarming preventable threat to society. 
 
Here I summarize a recent study that investigated the effects of long-term testosterone treatment – up to 8 years - on weight loss and waist size in 411 testosterone deficient men with obesity classes I-III.[13]
 
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Real-life experience of continuous long-term testosterone therapy on anthropometric, endocrine and metabolic parameters for up to 10 years

While it is well documented that testosterone levels decline in aging men, recent studies show that in some cases obesity and impaired general health can be more influential causes of testosterone deficiency than chronological age and aging per se.[1, 2]
 
Here I present real-life results from a registry study which investigated the effects of continuous long-term testosterone therapy for up to 10 years on anthropometric (body measurements), endocrine and metabolic parameters in obese hypogonadal men.[3]
 
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Considering CoolSculpting in Las Vegas? Here are 5 Things You Should Know

  • Published in Fat Loss


For a lot of people, the brand new year marks the beginning of a fresh start to accomplish the resolutions and goals you have set for yourself. For many, this is the time to get serious about living a healthier lifestyle, including finally getting rid of the extra stubborn belly fat you’ve been wanting to shed off. Unfortunately for some, the last bit of stubborn fat seems to cling on no matter how hard you’ve been working out and eating right. If this applies to you, Coolsculpting may be the perfect solution you are looking for. However, before you book the first appointment available to schedule your Coolsculpting treatment, there are a few things to consider first.

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