Niacin - vitamin B3 - when taken in high dose acts as a powerful cholesterol drug. Niacin is unique among all available cholesterol drugs because it has beneficial effects across the entire lipid/lipoprotein spectrum, including the three components of atherogenic dyslipidemia.
Niacin is especially noteworthy because it is the most potent drug available for raising HDL levels.[1, 2] Besides boosting HDL levels, niacin also markedly lowers triglyceride levels while reducing LDL to a smaller degree.
The table below provides an overview of the effects of popular drugs and supplements on blood lipids.