Ageless Forever Anti-Aging News Blog

Monica

Monica

Medical Writer & Nutritionist

MSc Nutrition

University of Stockholm & Karolinska Institute, Sweden 

   Baylor University, TX, USA

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Testosterone Therapy in Men with Prostate Cancer – Yes or No?

Historically, prostate cancer – both active and treated - has been an absolute contraindication to testosterone therapy and – from a regulatory perspective – still is. The incidence of prostate cancer is higher in older men, in whom prostate cancer accounts for one in five new cancer diagnoses.[1]
 
Thanks to improvement in early detection and treatment of prostate cancer, prostate cancer mortality has decreased 50% during the past two decades, and more men are living with a history of prostate cancer. 
 
The aging of the male population and the increasing number of prostate cancer survivors have resulted in a significant increase in the number of men presenting with hypogonadism and treated prostate cancer. Therefore, it is important to consider the growing number of recent studies which have challenged the long-standing belief that prostate cancer is an absolute contraindication to testosterone therapy.[2-4]
 
Here I summarize the results of a notable study which investigated the effects of testosterone therapy in men with treated and untreated prostate cancer [5], and conclude with the latest recommendations on managing testosterone deficiency in men with history of prostate cancer.
 

How is anabolic steroid use different from testosterone replacement therapy?

One main reason testosterone replacement therapy (aka testosterone treatment) is surrounded by controversy is that testosterone can be abused, both in athletic populations and the general public.[1] Scientific evidence is undisputed that testosterone y potently enhances physical performance and increases muscle growth.[1-3]
 
The ethical issue of fair play in sports, coupled with the well-known adverse health effects of supra-physiological doses of anabolic steroids [4-14], has given medically legit testosterone replacement therapy (aka TRT, testosterone therapy or testosterone treatment) a bad reputation and is depriving many suffering men with testosterone deficiency from receiving medically needed testosterone treatment.[15] 
 
In this article I will point out the salient differences between use testosterone replacement therapy – a.k.a. testosterone therapy or testosterone treatment - and abuse of anabolic steroids, and explain why testosterone treatment - which per definition is medically provided and supervised - has no parallel with abuse of anabolic steroids.
 
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Dr. Pierce's Medical Organization Affiliations

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